He should know that better than us, we are further away from the war. Possibly even going to Iraq first would be an option.
However, now I am reminded that Syria has banned all males 18-42 from leaving the country. So, it isnt easy, you basically have to escape through smuggle-lines/unguarded border.
EDIT: If I may speculate, the safest option would be to get to the coast and take a ship to anywhere that isnt Syria.
Another EDIT: Try to go to the kurdish areas, they will probably let you go to Turkey or Iraq.
Couldn't you dress yourself as a highly religious woman (using a burka)? You wear an attire covering your entire body, right? Not sure what rights religious people enjoy, but maybe you could pass as a woman.
Someone would stop you somewhere and ask WTF are you woman doing without your man, wait a minute, are you really a woman? Bang. Better be safe than sorry.
Also I dont believe it is very common with burkas in Syria.