I usually open them up in a new project just to create a lossless input video to work with in After Effects, and use that (if I use image sequence directly, DaVinci Resolve acts in weird ways).
Right, calling it technically lossless is wrong but 422 HQ gives impressive results so I we can probably safely say that it is "practically" lossless.
In DaVinci Resolve, many tools go awry with image sequences: for example temporal noise reduction simply doesn't work with a compound clip with image sequences, I also remember having problems with caching performance. I have a few very strange/buggy problems with Resolve though I love color grading with it regardless, so I want to avoid the buggy sides of Resolve (as it's one of the buggiest software I've ever used) but use the upsides of it (grading and some OpenFX filters).
I usually open them up in a new project just to create a lossless input video to work with in After Effects, and use that (if I use image sequence directly, DaVinci Resolve acts in weird ways).
ffmpeg might ease that AE part.