I really hope the work Valve is doing with Proton will help to get Office (no, the browser versions aren't a substitute), Adobe software and Touchdesigner working on Linux. I don't game, and would love to switch to Linux but I need those apps to work on it.
Microsoft could at least stop actively trying to break O365 on Wine, which I believe it is doing. I have heard rumors (albeit unsourced ones) that MS is trying to bring Outlook over first.
I think that's quite unlikely, most games use a fairly small subset of the Windows APIs, if non-game applications currently don't work then it's unlikely that the situation for those applications will be improved by better game compatibility.