I've personally been running ZFS with LZ4, where checksums handle corruption. Another upside is that LZ4 is fast enough to actually improve I/O throughput, since overhead is negligible. On my jail/container/vm datasets I've seen space reduction upwards 80%, with backup-datasets I've seen around 30% reduction.

Another possibility is data deduplication, which is useful if you have plenty of RAM. You can deduplicate across files on block level. However I have only used it sporadically due to the high ram usage.